DIVISION OF NEPHROLOGY    

DEPARTMENT   OF   MEDICINE,   UNIVERSITY OF TEXAS    HEALTH SCIENCE CENTER   AT   SAN ANTONIO

 
               
 
       
 
Click authors' names to see abstract at PubMed

1. Abboud HE. Growth factors and diabetic nephrology: an overview. Kidney Int Suppl 1997:60:S3-6.
 

2. Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 2000:275(26):19906-12.
 

3. Abboud SL, Woodruff KA, Choudhury GG. Retroviral-mediated gene transfer of CSF-1 into op/op stromal cells to correct defective in vitro osteoclastogenesis. J Cell Physiol 1998:176(2):323-31.
 

4. Ahuja SS, Reddick RL, Sato N, Montalbo E, Kostecki V, Zhao W, Dolan MJ, Melby PC, Ahuja SK. Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection. J Immunol 1999:163(7):3890-7.
 

5. Ahuja SS. Genetic engineering of dendritic cells using retrovirus-based gene transfer techniques. Methods Mol Biol 2001:156:79-87.
 

6. Ahuja SS. In vitro generation of functional human and murine dendritic cells. Methods Mol Biol 2001:156:67-77.
 

7. Bardgette J, Abboud HE, Choudhury GG. Activation of STAT1 alpha by phosphatase inhibitor vanadate in glomerular mesangial cells: involvement of tyrosine and serine phosphorylation. J Recept Signal Transduct Res 1999:19(5):865-84.
 

8. Barnes JL, Woodruff KA, Levine SP, Abboud HE. Inhibition of mesangial cell proliferation by platelet factor 4. J Am Soc Nephrol 1996:7(7):991-8.
 

9. Barnes JL. Platelets in glomerular disease. Nephron 1997:77(4):378-93.
 

10. Barnes VL, Musa J, Mitchell RJ, Barnes JL. Expression of embryonic fibronectin isoform EIIIA parallels alpha-smooth muscle actin in maturing and diseased kidney. J Histochem Cytochem 1999:47(6):787-98.
 

11. Bhandari BK, Feliers D, Duraisamy S, Stewart JL, Gingras AC, Abboud HE, Choudhury GG, Sonenberg N, Kasinath BS. Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells. Kidney Int 2001:59(3):866-75.
 

12. Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH. A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein. Proc Natl Acad Sci U S A 1997:94(17):9040-5.
 

13. Chen CF, Chen Y, Dai K, Chen PL, Riley DJ, Lee WH. A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. Mol Cell Biol 1996:16(9):4691-9.
 

14. Chen CF, Li S, Chen Y, Chen PL, Sharp ZD, Lee WH. The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor. J Biol Chem 1996:271(51):32863-8.
 

15. Chen PL, Chen CF, Chen Y, Xiao J, Sharp ZD, Lee WH. The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment. Proc Natl Acad Sci U S A 1998:95(9):5287-92.
 

16. Chen PL, Riley DJ, Chen-Kiang S, Lee WH. Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6. Proc Natl Acad Sci U S A 1996:93(1):465-9.
 

17. Chen Y, Chen PL, Chen CF, Sharp ZD, Lee WH. Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus. Proc Natl Acad Sci U S A 1999:96(8):4443-8.
 

18. Chen Y, Farmer AA, Chen CF, Jones DC, Chen PL, Lee WH. BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner. Cancer Res 1996:56(14):3168-72.
 

19. Chen Y, Lee WH, Chew HK. Emerging roles of BRCA1 in transcriptional regulation and DNA repair. J Cell Physiol 1999:181(3):385-92.
 

20. Chen Y, Riley DJ, Chen PL, Lee WH. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol Cell Biol 1997:17(10):6049-56.
 

21. Chen Y, Sharp ZD, Lee WH. HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins. J Biol Chem 1997:272(38):24081-7.
 

22. Choudhury GG, Ghosh-Choudhury N, Abboud HE. Association and direct activation of signal transducer and activator of transcription1alpha by platelet-derived growth factor receptor. J Clin Invest 1998:101(12):2751-60.
 

23. Choudhury GG, Grandaliano G, Jin DC, Katz MS, Abboud HE. Activation of PLC and PI 3 kinase by PDGF receptor alpha is not sufficient for mitogenesis and migration in mesangial cells. Kidney Int 2000:57(3):908-17.
 

24. Choudhury GG, Karamitsos C, Hernandez J, Gentilini A, Bardgette J, Abboud HE. PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF. Am J Physiol 1997:273(6 Pt 2):F931-8.
 

25. Choudhury GG, Marra F, Abboud HE. Thrombin stimulates association of src homology domain containing adaptor protein Nck with pp125FAK. Am J Physiol 1996:270(2 Pt 2):F295-300.
 

26. Choudhury GG, Marra F, Kiyomoto H, Abboud HE. PDGF stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells. Kidney Int 1996:49(1):19-25.
 

27. Choudhury GG. Akt Serine Threonine Kinase Regulates Platelet-derived Growth Factor-induced DNA Synthesis in Glomerular Mesangial Cells. REGULATION OF c-fos AND p27kip1 GENE EXPRESSION. J Biol Chem 2001:276(38):35636-43.
 

28. Feliers D, Duraisamy S, Faulkner JL, Duch J, Lee AV, Abboud HE, Choudhury GG, Kasinath BS. Activation of renal signaling pathways in db/db mice with type 2 diabetes. Kidney Int 2001:60(2):495-504.
 

29. Feliers D, Woodruff K, Abboud S. Potential role of insulin-like growth factor binding protein-4 in the uncoupling of bone turnover in multiple myeloma. Br J Haematol 1999:104(4):715-22.
 

30. Feng JQ, Chen D, Ghosh-Choudhury N, Esparza J, Mundy GR, Harris SE. Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoter. Biochim Biophys Acta 1997:1350(1):47-52.
 

31. Gentilini A, Feliers D, Pinzani M, Woodruff K, Abboud S. Characterization and regulation of insulin-like growth factor binding proteins in human hepatic stellate cells. J Cell Physiol 1998:174(2):240-50.
 

32. Ghosh Choudhury G, Ricono JM. Increased effect of interferon gamma on PDGF-induced c-fos gene transcription in glomerular mesangial cells: differential effect of the transcriptional coactivator CBP on STAT1alpha activation. Biochem Biophys Res Commun 2000:273(3):1069-77.
 

33. Ghosh-Choudhury N, Harris MA, Wozney J, Mundy GR, Harris SE. Clonal osteoblastic cell lines from p53 null mouse calvariae are immortalized and dependent on bone morphogenetic protein 2 for mature osteoblastic phenotype. Biochem Biophys Res Commun 1997:231(1):196-202.
 

34. Ghosh-Choudhury N, Windle JJ, Koop BA, Harris MA, Guerrero DL, Wozney JM, Mundy GR, Harris SE. Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice. Endocrinology 1996:137(1):331-9.
 

35. Gonzalez E, Bamshad M, Sato N, Mummidi S, Dhanda R, Catano G, Cabrera S, McBride M, Cao XH, Merrill G, O'Connell P, Bowden DW, Freedman BI, Anderson SA, Walter EA, Evans JS, Stephan KT, Clark RA, Tyagi S, Ahuja SS, Dolan MJ, Ahuja SK. Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proc Natl Acad Sci U S A 1999:96(21):12004-9.
 

36. Gooch JL, Christy B, Yee D. STAT6 Mediates Interleukin-4 Growth Inhibition in Human Breast Cancer Cells. Neoplasia 2002:4(4):324-31.
 

37. Gooch JL, Tang Y, Ricono JM, Abboud HE. Insulin-like growth factor-I induces renal cell hypertrophy via a calcineurin-dependent mechanism.
 

38. Gorin Y, Kim NH, Feliers D, Bhandari B, Choudhury GG, Abboud HE. Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase. FASEB J 2001:15(11):1909-20.
 

39. Grandaliano G, Choudhury GG, Poptic E, Woodruff K, Barnes JL, Abboud HE. Thrombin regulates PDGF expression in bovine glomerular endothelial cells. J Am Soc Nephrol 1998:9(4):583-9.
 

40. Grellier P, Feliers D, Yee D, Woodruff K, Abboud SL. Interaction between insulin-like growth factor-I and insulin-like growth factor-binding proteins in TC-1 stromal cells. J Endocrinol 1996:149(3):519-29.
 

41. Ha TS, Barnes JL, Stewart JL, Ko CW, Miner JH, Abrahamson DR, Sanes JR, Kasinath BS. Regulation of renal laminin in mice with type II diabetes. J Am Soc Nephrol 1999:10(9):1931-9.
 

42. Johnson LZ, Martinez I, Fernandez MC, Davis CP, Kasinath BS. Successful treatment of valproic acid overdose with hemodialysis. Am J Kidney Dis 1999:33(4):786-9.
 

43. Kasinath BS, Grellier P, Choudhury GG, Abboud SL. Regulation of basement membrane heparan sulfate proteoglycan, perlecan, gene expression in glomerular epithelial cells by high glucose medium. J Cell Physiol 1996:167(1):131-6.
 

44. Kasinath BS. Sifting the causes of microscopic hematuria. Hosp Pract (Off Ed) 1996:31(7):99-106, 109-10.
 

45. Ko CW, Bhandari B, Yee J, Terhune WC, Maldonado R, Kasinath BS. Cyclic AMP regulates basement membrane heparan sulfate proteoglycan, perlecan, metabolism in rat glomerular epithelial cells. Mol Cell Biochem 1996:162(1):65-73.
 

46. Li SL, Schlegel W, Valente AJ, Clark RA. Critical flanking sequences of PU.1 binding sites in myeloid-specific promoters. J Biol Chem 1999:274(45):32453-60.
 

47. Li SL, Valente AJ, Qiang M, Schlegel W, Gamez M, Clark RA. Multiple PU.1 sites cooperate in the regulation of p40(phox) transcription during granulocytic differentiation of myeloid cells. Blood 2002:99(12):4578-87.
 

48. Li SL, Valente AJ, Wang L, Gamez MJ, Clark RA.Transcriptional regulation of the p67{super} phox gene: Role of AP-1 in concert with myeloid-specific transcription factors.
 

49. Li SL, Valente AJ, Zhao SJ, Clark RA. PU.1 is essential for p47(phox) promoter activity in myeloid cells. J Biol Chem 1997:272(28):17802-9.
 

50. Lichtenstein MJ, Pruski LA, Marshall CE, Blalock CL, Murphy DL, Plaetke R, Lee S. The Positively Aging teaching materials improve middle school students' images of older people. Gerontologist 2001:41(3):322-32.
 

51. Marra F, Bonewald LF, Park-Snyder S, Park IS, Woodruff KA, Abboud HE. Characterization and regulation of the latent transforming growth factor-beta complex secreted by vascular pericytes. J Cell Physiol 1996:166(3):537-46.
 

52. Marra F, Choudhury GG, Abboud HE. Interferon-gamma-mediated activation of STAT1alpha regulates growth factor-induced mitogenesis. J Clin Invest 1996:98(5):1218-30.
 

53. McCann UG 2nd, Rabito F, Shah M, Nolan CR 3rd, Lee M. Acute renal failure complicating nonfulminant hepatitis A. West J Med 1996:165(5):308-10.
 

54. Mummidi S, Ahuja SS, Gonzalez E, Anderson SA, Santiago EN, Stephan KT, Craig FE, O'Connell P, Tryon V, Clark RA, Dolan MJ, Ahuja SK. Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression. Nat Med 1998:4(7):786-93.
 

55. Mummidi S, Ahuja SS, McDaniel BL, Ahuja SK. The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons. J Biol Chem 1997:272(49):30662-71.
 

56. Mummidi S, Bamshad M, Ahuja SS, Gonzalez E, Feuillet PM, Begum K, Galvis MC, Kostecki V, Valente AJ, Murthy KK, Haro L, Dolan MJ, Allan JS, Ahuja SK. Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus. J Biol Chem. 2000 Jun 23;275(25):18946-61.
 

57. Nikitin AY, Riley DJ, Lee WH. A paradigm for cancer treatment using the retinoblastoma gene in a mouse model. Ann N Y Acad Sci 1999:886:12-22.
 

58. Nikitin AY, Riley DJ, Lee WH. Earlier onset of melanotroph carcinogenesis in mice with inherited mutant paternal allele of the retinoblastoma gene. Cancer Res 1997:57(19):4274-8.
 

59. Olsen JG, Salih MA, Harrison JL, Herrera I, Luther MF, Kalu DN, Lifschitz MD, Katz MS, Yeh CK. Modulation by food restriction of intracellular calcium signaling in parotid acinar cells of aging Fischer 344 rats. J Gerontol A Biol Sci Med Sci 1997:52(3):B152-8.
 

60. Park IS, Kiyomoto H, Abboud SL, Abboud HE. Expression of transforming growth factor-beta and type IV collagen in early streptozotocin-induced diabetes. Diabetes 1997:46(3):473-80.
 

61. Park IS, Kiyomoto H, Alvarez F, Xu YC, Abboud HE, Abboud SL. Preferential expression of insulin-like growth factor binding proteins-1, -3, and -5 during early diabetic renal hypertrophy in rats. Am J Kidney Dis 1998:32(6):1000-10.
 

62. Pergola PE, Kancharla A, Riley DJ. Kidney transplantation during the first trimester of pregnancy: immunosuppression with mycophenolate mofetil, tacrolimus, and prednisone. Transplantation 2001:71(7):994-7.
 

63. Ricono JM, Arar M, Choudhury GG, Abboud HE. Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells. Am J Physiol Renal Physiol 2002:282(2):F211-9.
 

64. Ricono JM, Arar M, Ghosh Choudhury G, Abboud HE. Effect of Platelet-Derived Growth Factor (PDGF) Isoforms in Rat Metanephric Mesenchymal Cells.
 

65. Riley DJ, Liu CY, Lee WH. Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression. Mol Cell Biol 1997:17(12):7342-52.
 

66. Riley DJ, Nikitin AY, Lee WH. Adenovirus-mediated retinoblastoma gene therapy suppresses spontaneous pituitary melanotroph tumors in Rb+/- mice. Nat Med 1996:2(12):1316-21.
 

67. Sato N, Kuziel WA, Melby PC, Reddick RL, Kostecki V, Zhao W, Maeda N, Ahuja SK, Ahuja SS. Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice. J Immunol 1999:163(10):5519-25.
 

68. Senthil D, Faulkner JL, Choudhury GG, Abboud HE, Kasinath BS. Angiotensin II inhibits insulin-stimulated phosphorylation of eukaryotic initiation factor 4E-binding protein-1 in proximal tubular epithelial cells. Biochem J 2001:360(Pt 1):87-95.
 

69. Simon M, Cleary TG, Hernandez JD, Abboud HE. Shiga toxin 1 elicits diverse biologic responses in mesangial cells. Kidney Int 1998:54(4):1117-27.
 

70. Simon M, Feliers D, Arar M, Bhandari B, Abboud HE. Cloning of the 5'-flanking region of the murine bone morphogenetic protein-7 gene. Mol Cell Biochem 2002:233(1-2):31-7.
 

71. Valente AJ, Xie JF, Abramova MA, Wenzel UO, Abboud HE, Graves DT. A complex element regulates IFN-gamma-stimulated monocyte chemoattractant protein-1 gene transcription. J Immunol 1998:161(7):3719-28.
 

72. Zheng L, Chen Y, Lee WH. Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins. Mol Cell Biol 1999:19(8):5417-28.
 

73. Zheng L, Chen Y, Riley DJ, Chen PL, Lee WH. Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p. Mol Cell Biol 2000:20(10):3529-37.
 

74. Zhong Q, Chen CF, Chen Y, Chen PL, Lee WH. Identification of cellular TSG101 protein in multiple human breast cancer cell lines. Cancer Res 1997:57(19):4225-8.
 

75. Zhong Q, Chen CF, Li S, Chen Y, Wang CC, Xiao J, Chen PL, Sharp ZD, Lee WH. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science 1999:285(5428):747-50.
 

76. Zhong Q, Chen Y, Jones D, Lee WH. Perturbation of TSG101 protein affects cell cycle progression. Cancer Res 1998:58(13):2699-702.